Adherence Study of Outpatient with Diabetes Mellitus in Sidoarjo District General Hospital

efer momento, Angelica Kresnamurti, Dyah Ayu Febiyanti


Diabetes mellitus is a metabolic disease which is a collection of symptoms that arise because of increase of a person's blood glucose levels above normal values and requires regular treatment. Patient adherence is very important to reduce the risk of the occurrence of complications in diabetes mellitus patient. This research aims to determine the patient adherence in taking diabetes medication with two different methods, namely Pill count and MMAS-8, as well as see correlation between the two methods. The method of this research is using cross sectional with non-probability sampling methods, conducted on 21 outpatients in Sidoarjo Hospital. Based on the results of the study, adherence measurement using pill count was obtained 14 respondents adherent (66.67%) and non-adherent respondents was 7 (33.33%), while the result of MMAS-8 method was 8 respondents (38.10%) with high adherence, 10 respondents (47.62%) with intermediate adherence and 3 respondents (14.29%) with poor adherence. Comparison between methods of pill count and MMAS-8 carried out using the SPSS statistical program, and obtained results by as much as 50% has the value expected count less than 5, so it does not qualify to do test chi square (χ2). Therefore, the fisher exact test was done as the alternative way by viewing the exact-sig value in the column fisher exact-test and obtained the value of 0.247 with a significance value of 0.05 so there was no correlation between the measurements result of adherence with the method MMAS-8 and pill count.


Diabetes mellitus, Pill count, MMAS-8

Full Text:



Adisa, R., Alutundu, M.B. & Fakeye, T.O., 2009, Factors contributing to nonadherence to oral hypoglycemic medications among ambulatory type 2 diabetes patients in Southwestern Nigeria, Pharmacy Practice, 7(3): 163-169.

Astuti, Yani Praja. (2012). Pengaruh Persepsi Keadilan Pajakterhadap Perilaku Kepatuhan Wajib Pajak Badan Di Indonesia. Universitas Indonesia.

Donald, M., Dower, J., Coll, J. R., Baker, P., Mukandi, B. & Doi, S. A. 2013. Mental health issue decrease diabetes-specific quality of life independent of glycaemic controland complications: findings from Australia’s living with diabetes cohort study. BioMed Central, 11, 1-8.

Fairman, K., dan Motheral, B. 2000. Medication Adherence: Which Measure is Right for Your Program. J Manages Care Pharm : 499-504 46.

Farmer, K. C. 1999. Methods for Measuring and Monitoring Medication Regimen Adherence in Clinical Trials and Clinical Practice. Clinical Therapeutics, 21 (6) : 1071-1090.

Grymonpre, R.E., Didur, C.D., Montgomery, P.R., Sitar, D.S., 1998, Pill Count, Self-Report, and Pharmacy Claims Data to Measure Medication Adherence in the Elderly, The Annals of Pharmacotherapy, 32: 749-754.

HIV Clinical Resources. 2005. Appendix X: Advantages and Disadvantages of Adherence Measures, [Online] Available from : [Accessed: 15th Oktober 2016].

Jelantik, G.M.G. 2014. Hubungan Faktor Resiko Umur, Jenis Kelamin, Kegemukan dan Hipertensi dengan Kejadian Diabetes Mellitus tipe II di Wilayah Kerja Puskesmas Mataram. Jurnal Kesehatan. Denpasar. Media Bina Ilmiah. Volume 8, No 1, Februari 2014.

Kementerian Kesehatan RI. 2007. Riset Kesehatan Dasar (RISKESDAS) 2007. Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. Jakarta: Kementerian Kesehatan RI.

Kementerian Kesehatan RI. 2013. Riset Kesehatan Dasar (RISKESDAS) 2013. Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. Jakarta: Kementerian Kesehatan RI.

Lee, J. Y., Kusek, J. W., Greene, P. G., Bernhard, S., Norris, K., Smith, D., et al. 1996. Assessing Medication Adherence by Pill Count and Electronic Monitoring in the African American Study of Kidney Disease and Hypertension (AASK) Pilot Study, American Journal of Hypertension, 9 (8), 719-725.

Marhanis, S.O., dan San, K.L., 2014. Diabetes Knowledge And Medication Adherence Among Geriatric Patient With Type 2 Diabetes Mellitus. International Journal of Pharmacy and Pharmaceutical Sciences. 6 : 103-104.

Morisky, D. E., Ang, A., Krousel-Wood, M., dan Ward, H. J., 2008, Predictive Validity of A Medication Adherence Measure in an Outpatient Setting, J Clin Hypertens (Greenwich), 10 (5) : 348-354.

Morris, L. S., dan Schulz, R. M. 1992. Patient Compliance: An Overview, Journal of Clinical Pharmcay and Therapeutics, 17 : 183-195.

Notoatmodjo, S. 2012. Metodologi Penelitian Kesehatan. PT. Rineka Cipta, Jakarta.

Saepudin., Padmasari, S., Hidayanti, P., Ningsih, E. S. 2013. Kepatuhan Penggunaan Obat pada Pasien Hipertensi di Puskesmas, Jurnal Farmasi Indonesia, 6 (4): 246-253.

Yanita, Bella dan Kurniawaty, Evi. 2016. Faktor-Faktor yang Berhubungan dengan Kejadian Diabetes Melitus Tipe II. Majority, vol. 5 (2). Fakultas Kedokteran. Universitas Lampung.


  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a  Creative Commons Attribution-NonCommercial 4.0 International License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

 Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.