IDENTIFIKASI FITOKIMIA DAUN GANDARUSA (JUSTICIA GENDARUSSA L.) ASAL KABUPATEN PANGKEP
Analisis Kandungan Senyawa Aktif Menggunakan Metode Kromatografi dan Uji Fitokimia
DOI:
https://doi.org/10.30649/pst.v5i1.395Keywords:
Extraction, Fractionation, Justicia gendarussa, Phytochemistry, YieldAbstract
Gandarusa leaves (Justicia gendarussa L.) are recognized as medicinal plants rich in various active phytochemicals. Extraction was carried out using the maceration method with 96% ethanol, followed by evaporation with a rotary evaporator to obtain a concentrated extract. Fractionation was performed using liquid-liquid partitioning with n-hexane and ethyl acetate to separate compounds based on polarity. The results revealed the ethyl acetate fraction had the highest yield at 20.8%, followed by the n-hexane fraction at 20%. Phytochemical identification using thin-layer chromatography confirmed the presence of alkaloids, flavonoids, and steroids. UV-Vis spectrophotometry analysis showed the total flavonoid content reached 0.741 mg/L based on the quercetin standard curve. These findings highlight the potential of gandarusa leaves as a promising source of bioactive compounds for pharmaceutical development.
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